This is true for high-income countries. The third, and most deadly one, affected Asia, Europe, North America and Africa. Cholera is an intestinal disease caused by a strain of the bacterium Vibrio cholerae and can cause death within hours after the first symptoms if there is no treatment. [14] Children are also more susceptible, with two- to four-year-olds having the highest rates of infection. [74], The word cholera is from Greek: χολέρα kholera from χολή kholē "bile". There were three large cholera outbreaks in the 1800s, which can be attributed to Vibrio cholerae's spread through interior waterways like the Erie Canal and routes along the Eastern Seaboard. [80] The third pandemic erupted in 1846, persisted until 1860, extended to North Africa, and reached South America, for the first time specifically affecting Brazil. The next video describes the cholera epidemic in Haiti in 2010. London 1987, Huber, Valeska. The investigation continued. [citation needed], Stool and swab samples collected in the acute stage of the disease, before antibiotics have been administered, are the most useful specimens for laboratory diagnosis. ", FDA Product Approval – Immunization Action Coalition, "Vaccines for preventing cholera: killed whole cell or other subunit vaccines (injected)", "News from the World Health Organization", "The cholera pandemic, still with us after half a century: time to rethink", "The scenario approach for countries considering the addition of oral cholera vaccination in cholera preparedness and control plans", THE TREATMENT OF DIARRHOEA, A manual for physicians and other senior health workers, "Community Health Worker Training Materials for Cholera Prevention and Control", "Oral Rehydration Solutions: Made at Home", "First steps for managing an outbreak of acute diarrhea", "Antimicrobial drugs for treating cholera", "Oral rehydration salts, zinc supplement and rota virus vaccine in the management of childhood acute diarrhea", "Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010", "Vibrio cholerae and cholera: out of the water and into the host", "The horrors of Yemen's spiralling cholera crisis", "Yemen Now Faces 'The Worst Cholera Outbreak In The World,' U.N. Says", "All Entries by BONDT, Jacob de, Jacobus Bontius: HistoryofMedicine.com", "Cholera – Vibrio cholerae infection | Cholera | CDC", Epidemics and pandemics: their impacts on human history, "The history of the flannel binder and cholera belt", "Cholera Infantum, Tomatoes Will Relieve", "The diffusion of cholera in the United States in the nineteenth century", "Osservazioni microscopiche e deduzioni patologiche sul cholera asiatico", "Magic bullet: the history of oral rehydration therapy", "Albert Lasker Clinical Medical Research Award", "Host-induced epidemic spread of the cholera bacterium", "Cholera epidemics in Bangladesh: 1985-1991", "Media, institutions, and government action: prevention vs. palliation in the time of cholera", "The 2010 cholera outbreak in Haiti: how science solved a controversy", The Singapore Free Press and Mercantile Advertiser, 25 March 1893, Page 2, "Identification of cholera hotspots in Zambia: A spatiotemporal analysis of cholera data from 2008 to 2017", "Cholera Epidemic - Lusaka, Zambia, October 2017-May 2018", "Emergency Plan of Action Final Report Zambia: Cholera Outbreak Lusaka", "Cholera epidemic in and around Kolkata, India: endemicity and management", "Cholera: Calamitous Past, Ominous Future", https://en.wikipedia.org/w/index.php?title=Cholera&oldid=998487992, Articles lacking reliable references from December 2013, Articles with dead external links from June 2018, Wikipedia pages semi-protected against vandalism, Articles containing potentially dated statements from 2010, All articles containing potentially dated statements, Articles with unsourced statements from July 2015, Articles with unsourced statements from December 2013, All articles with vague or ambiguous time, Articles with unsourced statements from August 2020, Articles containing potentially dated statements from 2018, Wikipedia articles incorporating a citation from the 1911 Encyclopaedia Britannica with Wikisource reference, Wikipedia medicine articles ready to translate, Creative Commons Attribution-ShareAlike License, Sterilization: Proper disposal and treatment of all materials that may have come into contact with cholera victims' feces (e.g., clothing, bedding, etc.) In 1854 deaths a year 2011, 101 obtained their water from the United States. 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